Masaomi Nangaku (The University of Tokyo Graduate School of Medicine)

2012- present; Professor and Head, Division of Nephrology and Endocrinology, the University of Tokyo Graduate School of Medicine

2023- present; Dean, the University of Tokyo Graduate School of Medicine

2019- 2022; President of the APSN

2023- 2025; President of the ISN

2022- present; President of the JSN-

His principal interests in nephrology include diabetic kidney disease and oxygen biology in the kidney including anemia in CKD. He is also a chair of the “Moonshot Research and Development Program” of telemedicine, which sets ambitious goals and promotes challenging R&D projects with the aim of resolving difficult societal issues while bringing together the wisdom of researchers from all over the world.

1. Agarwal R, Green JB, Heerspink HJL, Mann JFE, McGill JB, Mottl AK, Rosenstock J, Rossing P, Vaduganathan M, Brinker M, Edfors R, Li N, Scheerer MF, Scott C, Nangaku M; CONFIDENCE Investigators. Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes. N Engl J Med 393, 533-543, 2025

2. Mimura I, Nangaku M, Kanki Y, Tsutsumi S, Inoue T, Kohro T, Yamamoto S, Fujita T, Shimamura T, Suehiro JI, Taguchi A, Kobayashi M, Tanimura K, Inagaki T, Tanaka T, Hamakubo T, Sakai J, Aburatani H, Kodama T, Wada Y. Dynamic change of the chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of HIF1 and KDM3A. Mol Cell Biol 32, 3018-32, 2012

3. Nangaku M. Chronic hypoxia and tubulointerstitial injury. A final common pathway to end stage renal failure. J Am Soc Nephrol 17, 17-25, 2006

4. Tanaka T, Miyata T, Inagi R, Fujita T, Nangaku M. Hypoxia in renal disease with proteinuria and/or glomerular hypertension. Am J Pathol 165, 1979-1992, 2004

5. Matsumoto M, Makino Y, Tanaka T, Tanaka H, Ishizaka N, Noiri E, Fujita T, Nangaku M. Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats. J Am Soc Nephrol 14, 1825-32, 2003