JAESEOK YANG (Severance Hospital)

KSN 2025

Curriculum Vitae

Name JAESEOK YANG

Country Korea, Republic of
Affiliation Severance Hospital
Department Internal Medicine-Nephrology
Educational Background & Professional Career

M.D.: Seoul National University Medical College

Ph.D. (Immunology): Seoul National University Medical College

Postdoctoral fellow (transplantation immunology): University of Pennsylvania

Professor: Transplantation center, Seoul National University Hospital (2009- 2021.8)

Professor: Division of Nephrology, Department of Internal Medicine, Yonsei University (2021.9-current)

Research Interests

Professor Yang has participated in kidney transplant patient care as well as transplant immunologic research as a transplant physician and immunologist.

Main research interest includes roles of immunosuppressive cells and engineered cell therapy in transplantation, basic & translational research about ABO blood group-incompatible transplantation, and immune regulation in xenotransplantation.

He is also involved in kidney transplant cohort study with big data and multiomics as the Principal Investigator, Korean Organ Transplantation Registry (KOTRY).

Publications

Choi HR, Piao H, Atriardi SR, Kang I, Chang T, Kim S, Jang JY, Lee GM, Jung KC, Mardhiyah H, Machmud FI, Park J, Woo SK*, Yang J*, Kim CH*. Selective Depletion of ABO-Responsive B Cells by T Cell-Engaging Bispecific Antibody Conjugates for ABOi Transplantation. Blood 2026;147(17):1928-1940.

Yan JJ, Kim H, Kim B, Piao H, Jang JY, Kang TK, Lee WB, Kim D, Jo S, Shin D, Abuzar SM, Kim ML, Yang J*, Jon S. Synthetic Bilirubin-Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune-Modulating Activity. Adv Healthc Mater. 2025 Mar;14(7):e2403846.

Han DK, Hong SK, Yun IH, Yan JJ, Park JS, Kim SW, Seok SH, Kim H, Ji G, Choi Y, Lee KW, Suh KS, Yang J*, Yi NJ*. Anti-ICAM-1 mono-maintenance therapy induced long-term liver allograft survival without chronic rejection. Am J Transplant 2024;24(10):1772-1783.

Yoo EJ, Oh K-H, Piao Honglin, Kang HJ, Jeong GW, Park H, Lee CJ, Ryu H, Yang SH, Kim M-G, Kim DK, Park SH, Lim BJ, Lee SM, Park CY, Choi SY, Lee-Kwon W, Yang J*, Kwon HM*. Macrophage TonEBP promotes systemic lupus erythematosus and renal injury via damage-induced signaling pathways. Kidney Int 2023;104(1):163-180.

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