Hirotaka Komaba (Tokai University School of Medicine)

KSN 2025

Curriculum Vitae

Name Hirotaka Komaba

Country Japan
Affiliation Tokai University School of Medicine
Department Internal Medicine-Nephrology
Educational Background & Professional Career

2003: MD, Kobe University School of Medicine

2010: PhD, Kobe University Graduate School of Medicine

2013–2015: Visiting Assistant Professor, Harvard School of Dental Medicine

2024–present: Professor, Tokai University School of Medicine

Research Interests

CKD-MBD

Secondary hyperparathyroidism

FGF23–Klotho axis

Publications

Komaba H, Goto S, Fujii H, et al. Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients. Kidney Int 77: 232-238, 2010

Komaba H, Fukagawa M. The role of FGF23 in CKD: with or without Klotho. Nat Rev Nephrol 8: 484-490, 2012

Kir S, Komaba H, Garcia AP, et al. PTH/PTHrP receptor mediates cachexia in models of kidney failure and cancer. Cell Metab 23: 315-323, 2016

Komaba H, Hamano T, Fujii N, et al. Parathyroidectomy vs cinacalcet among patients undergoing hemodialysis. J Clin Endocrinol Metab 107: 2016-2025, 2022

Komaba H, Imaizumi T, Hamano T, et al. Lower Parathyroid Hormone Levels are Associated With Reduced Fracture Risk in Japanese Patients on Hemodialysis, Kidney Int Rep 9: 2956-2969 2024

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